High Performance computing improvements on bioinformatics consistency-based multiple sequence alignment tools
نویسندگان
چکیده
منابع مشابه
High Performance computing improvements on bioinformatics consistency-based multiple sequence alignment tools
Multiple Sequence Alignment (MSA) is essential for a wide range of applications in Bioinformatics. Traditionally, the alignment accuracy was the main metric used to evaluate the goodness of MSA tools. However, with the growth of sequencing data, other features, such as performance and the capacity to align larger datasets, are gaining strength. To achieve these new requirements, without affecti...
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To study gene evolution across a wide range of organisms, biologists need accurate tools for multiple sequence alignment of protein families. Obtaining accurate alignments, however, is a difficult computational problem because of not only the high computational cost but also the lack of proper objective functions for measuring alignment quality. In this paper, we introduce probabilistic consist...
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Multiple sequence alignments have primary role in several domains of modern molecular biology such as protein 3D structure/function prediction, phylogeny inference, molecular function, intermolecular interactions and many other common tasks in sequence analysis. Presently, many tools to construct multiple sequence alignments are available but none of them is accurate for all types of data sets....
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ژورنال
عنوان ژورنال: Parallel Computing
سال: 2015
ISSN: 0167-8191
DOI: 10.1016/j.parco.2014.09.010